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Depression is classified as a mood disorder. It may be described as feelings of sadness, loss, or anger that interfere with a person’s everyday activities. It’s also fairly common. Data from theCenters for Disease Control and Preventionestimates that 18.5 percent of American adults had symptoms of depression in any given 2-week period in 2019. Though depression and grief share some features, depression is different from grief felt after losing a loved one or sadness felt after a traumatic life event. Depression usually involves self-loathing or a loss of self-esteem, while grief typically does not. In grief, positive emotions and happy memories of the deceased typically accompany feelings of emotional pain. In major depressive disorder, the feelings of sadness are constant. People experience depression in different ways. It may interfere with your daily work, resulting in lost time and lower productivity. It can also influence relationships and some chronic health conditions. Conditions that can get worse due to depression include:
It’s important to realize that feeling down at times is a normal part of life. Sad and upsetting events happen to everyone. But if you’re feeling down or hopeless on a regular basis, you could be dealing with depression. Depression is considered a serious medical condition that can get worse without proper treatment. Depression symptomsDepression can be more than a constant state of sadness or feeling “blue.” Major depression can cause a variety of symptoms. Some affect your mood and others affect your body. Symptoms may also be ongoing or come and go. General signs and symptomsNot everyone with depression will experience the same symptoms. Symptoms can vary in severity, how often they happen, and how long they last. If you experience some of the following signs andsymptomsof depression nearly every day for at least 2 weeks, you may be living with depression:
The symptoms of depression can be experienced differently among males, females, teens, and children. Males may experience symptoms related to their:
Females may experience symptoms related to their:
Children may experiencesymptomsrelated to their:
Depression causesThere are several possible causes of depression. They can range from biological to circumstantial. Common causes include:
Risk factorscan be biochemical, medical, social, genetic, or circumstantial. Common risk factors include:
The causes of depression are often tied to other elements of your health. Treatment for depressionYou may successfully manage symptoms with one form of treatment, or you may find that a combination of treatments works best. It’s common to combine medical treatments and lifestyle therapies, including the following: MedicationsYour healthcare professional may prescribe: Selective serotonin reuptake inhibitors (SSRIs)SSRIs are the most commonly prescribed antidepressant medications and tend to have few side effects. They treat depression by increasing the availability of the neurotransmitter serotonin in your brain. SSRIs shouldwith certain drugs including monoamine oxidase inhibitors (MAOIs) and in some cases thioridazine or Orap (pimozide). People who are pregnant should talk to their healthcare professionals about the risks of taking SSRIs during pregnancy. You should alsouse cautionif you have narrow-angle glaucoma. Examples of SSRIs include citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), paroxetine (Paxil, Paxil XR, Pexeva), and sertraline (Zoloft). Serotonin and norepinephrine reuptake inhibitors (SNRIs)SNRIs treat depression by increasing the amount of the neurotransmitters serotonin and norepinephrine in your brain. SNRIs should not be taken with MAOIs. You should use caution if you have liver or kidney problems, or narrow-angle glaucoma. Examples of SNRIs include desvenlafaxine (Pristiq, Khedezla), duloxetine (Cymbalta, Irenka), levomilnacipran (Fetzima), milnacipran (Savella), and venlafaxine (Effexor XR). Tricyclic and tetracyclic antidepressantsTricyclic antidepressants (TCAs) and tetracyclic antidepressants (TECAs) treat depression by increasing the amount of the neurotransmitters serotonin and norepinephrine in your brain. TCAs can cause more side effects than SSRIs or SNRIs. Do not take TCAs or TECAs with MAOIs. Use with caution if you have narrow-angle glaucoma. Examples of tricyclic antidepressants include amitriptyline (Elavil), doxepin (Sinequan), imipramine (Tofranil), trimipramine (Surmontil), desipramine (Norpramin), nortriptyline (Pamelor, Aventyl), and protriptyline (Vivactil). Atypical antidepressantsNoradrenaline and dopamine reuptake inhibitors (NDRIs)These drugs can treat depression by increasing the levels of dopamine and noradrenaline in your brain. Examples of NDRIs include bupropion (Wellbutrin). Monoamine oxidase inhibitors (MAOIs)MAOIs treat depression byincreasing the levelsof norepinephrine, serotonin, dopamine, and tyramine in your brain. Due to side effects and, MAOIs are not the first choice for treating mental health disorders. They are typically used only if other medications are unsuccessful at treating depression. Examples of MAOIs include isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Emsam), tranylcypromine (Parnate). N-methyl D-aspartate (NMDA) antagonistsN-methyl-D-aspartate (NDMA) antagonistsby increasing levels of glutamate in the brain. Glutamate is a neurotransmitter believed to be involved in depression. NMDA antagonists are used only in patients who have not had success with other antidepressant treatments. The FDA has approved one NDMA medication,(Spravato), for the treatment of depression. Esketamine is a nasal spray that is only available through a restricted program called Spravato REMS. Patients may experience tiredness and dissociation (difficulty with attention, judgment, and thinking) after taking the medication. For this reason, esketamine is administered in a healthcare setting where a healthcare professional can monitor for sedation and dissociation. Each type of medication that’s used to treat depression has benefits and potential risks. PsychotherapySpeaking with a therapist can help you learn skills to cope with negative feelings. You may also benefit from family or group therapy sessions. Psychotherapy, also known as “talk therapy,” is when a person speaks to a trained therapist to identify and learn to cope with the factors that contribute to their mental health condition, such as depression. Psychotherapy hasbeen shownto be an effective treatment in improving symptoms in people with depression and other psychiatric disorders. Psychotherapy is often used alongside pharmaceutical treatment. There are many different types of psychotherapy, and some people respond better to one type than another. Cognitive behavioral therapy (CBT)In cognitive behavioral therapy (CBT), a therapist will work with you to uncover unhealthy patterns of thought and identify how they may be causing harmful behaviors, reactions, and beliefs about yourself. Your therapist might assign you “homework” where you practice replacing negative thoughts with more positive thoughts. Dialectical behavior therapy (DBT)Dialectical behavior therapy (DBT) is similar to CBT, but puts a specific emphasis on validation, or accepting uncomfortable thoughts, feelings, and behaviors, instead of fighting them. The theory is that by coming to terms with your harmful thoughts or emotions, you can accept that change is possible and make a recovery plan. Psychodynamic therapyPsychodynamic therapy is a form of talk therapy designed to help you better understand and cope with your day-to-day life. Psychodynamic therapy isbased on the ideathat your present-day reality is shaped by your unconscious, childhood experiences. In this form of therapy, your therapist will help you reflect and examine your childhood and experiences to help you understand and cope with your life. Looking for ways to support your mental health and well-being? Try Healthline’s FindCare tool to connect with mental health professionals nearby or virtually so you can get the care you need. Light therapyExposure to doses of white light can help regulate your mood and improve symptoms of depression. Light therapy is commonly used in seasonal affective disorder, which is now called major depressive disorder with seasonal pattern. Electroconvulsive therapy (ECT)Electroconvulsive therapy (ECT) uses electrical currents to induce a seizure, and has been shown to help people with clinical depression. It’s used in people with severe depression or depression that is resistant to other treatments or antidepressant medications. During an ECT procedure, you’ll receive an anesthetic agent which will put you to sleep for approximately 5 to 10 minutes. Your healthcare professional will place cardiac monitoring pads on your chest and four electrodes on specific areas of your head. They will then deliver short electrical pulses for a few seconds. You will neither convulse nor feel the electrical current and will awaken about 5 to 10 minutes after treatment. Side effects include headaches, nausea, muscle aches and soreness, and confusion or disorientation. Patients may also develop memory problems, but these usually reside in the weeks and months after treatment Alternative therapiesAsk your doctor about alternative therapies for depression. Many people choose to use alternative therapies alongside traditional psychotherapy and medication. Some examples include:
Natural remedies and lifestyle tipsExerciseAim for 30 minutes of physical activity 3 to 5 days a week. Exercise can increase your body’s production of endorphins, which are hormones that improve your mood. Avoid alcohol and substance useDrinking alcohol or misusing substances may make you feel better for a little bit. But in the long run, these substances can make depression and anxiety symptoms worse. Learn how to set limitsFeeling overwhelmed can worsen anxiety and depression symptoms. Setting boundaries in your professional and personal life can help you feel better. Take care of yourselfYou can also improve symptoms of depression by taking care of yourself. This includes getting plenty of sleep, eating a healthy diet, avoiding negative people, and participating in enjoyable activities. Sometimes depression doesn’t respond to medication. Your healthcare professional may recommend other treatment options if your symptoms don’t improve. These options include electroconvulsive therapy (ECT) or repetitive transcranial magnetic stimulation (rTMS) to treat depression and improve your mood. SupplementsSeveral types of supplements may have some positive effect on depression symptoms. S-adenosyl-L-methionine (SAMe)Someresearchsuggests this compound may ease symptoms of depression. The effects were best seen in people taking SSRIs. However, the results of this research is not conclusive and more research is needed. 5-hydroxytryptophan (5-HTP)5-HTPmay raiseserotonin levels in the brain, which could ease symptoms. Your body makes this chemical when you consume tryptophan, a building block of protein. However, more studies are needed. Omega-3 fatty acidsThese essential fats are important to neurological development and brain health. Adding omega-3 supplements to your dietmay helpreduce depression symptoms. However, there is some conflicting evidence and more research is needed. Always talk to your doctor before taking supplements, as they may interact with other medications or have negative effects. VitaminsVitamins are important to many bodily functions. Research suggests two vitamins are especially useful for easing symptoms of depression:
Many herbs, supplements, and vitamins claim to help ease symptoms of depression, but most haven’t shown themselves to be effective in clinical research. Learn about herbs, vitamins, and supplements that have shown some promise, and ask your healthcare professional if any are right for you. Depression testThere isn’t a single test to diagnose depression. But your healthcare provider can make a diagnosis based on your symptoms and a psychological evaluation. In most cases, they’ll ask a series of questions about your:
Because depression can be linked to other health problems, your healthcare professional may also conduct a physical examination and order blood work. Sometimes thyroid problems or a vitamin D deficiency can trigger symptoms of depression. It’s important not to ignore symptoms of depression. If your mood doesn’t improve or gets worse, seek medical help. Depression is a serious mental health illness with the potential for complications. If left untreated, complicationscan include:
Types of depressionDepression can be broken into categories depending on the severity of symptoms. Some people experience mild and temporary episodes, while others experience severe and ongoing depressive episodes. There are two main types: major depressive disorder and persistent depressive disorder. Major depressive disorderMajor depressive disorder (MDD) is the more severe form of depression. It’s characterized by persistent feelings of sadness, hopelessness, and worthlessness that don’t go away on their own. In order to be diagnosed with clinical depression, you must experience five or more of the following symptoms over a 2-week period:
There are different subtypes of major depressive disorder, which the American Psychiatric Association refers to as “specifiers.” Theseinclude:
Persistent depressive disorderPersistent depressive disorder (PDD) used to be called dysthymia. It’s a milder, but chronic, form of depression. In order for the diagnosis to be made, symptoms must last for at least2 years. PDD can affect your life more than major depression because it lasts for a longer period. It’s common for people with PDD to:
Depression can be treated successfully, but it’s important to stick to your treatment plan. Read more about why depression treatment is important. Living with depression can be difficult, but treatment can help improve your quality of life. Talk to your healthcare professional about possible options. The Healthline FindCare tool can provide options in your area if you don’t already have a doctor. Postpartum depressionPostpartum depression refers to depression that happens after childbirth. It is a common disorder after pregnancy, affecting1 in 9 new parents. It’s common for people to experience “baby blues,” or feelings of sadness or emptiness after childbirth. For many people, these symptoms go away in a couple of days. But if you feel sad, hopeless, or empty for longer than 2 weeks post-childbirth, you may have postpartum depression. Symptoms of postpartum depression can range from mild to severe and caninclude:
Postpartum depression is thought to betriggered bythe dramatic hormonal changes that take place after pregnancy. Bipolar depression occurs in certain types of bipolar disorder when a person experiences a depressive episode. Bipolar disorder is a mental disorder thatcausesdistinct changes in mood, energy, concentration, and the ability to carry out your day-to-day tasks. There are three types of bipolar disorder, all of which include periods known as manic episodes, where you feel extremely “up,” elated, or energized, and depressive episodes where you feel “down,” sad, or hopeless. If you have bipolar disorder, it can be hard to recognize the harmful effects of each “mood episode.” People having a depressive episodemay:
Symptoms during a depressive episode last every day for most of the day and can last for several days or weeks. If bipolar disorder is treated, many will experience fewer and less severe symptoms of depression, if they experience depressive episodes. These 7 treatments may help ease symptoms of bipolar depression. Depression and anxietyDepression and anxiety can occur in a person at the same time. In fact, research has shown that over70 percentof people with depressive disorders also have symptoms of anxiety. Though they’re thought to be caused by different things, depression and anxiety can produce several similar symptoms, which can include:
The two conditions also share some common treatments. Both anxiety and depression can be treated with:
If you think you’re experiencing symptoms of either of these conditions or both of them, make an appointment to talk with your healthcare professional. You can work with them to identify coexisting symptoms of anxiety and depression and how they can be treated. Depression and obsessive-compulsive disorder (OCD)Obsessive-compulsive disorder (OCD) is a type of anxiety disorder. It causes unwanted and repeated thoughts, urges, and fears (obsessions). These fears cause you to act out repeated behaviors or rituals (compulsions) that you hope will ease the stress caused by the obsessions. People diagnosed with OCD frequently find themselves in a loop of obsessions and compulsions. If you have these behaviors, you may feel isolated because of them. This can lead to withdrawal from friends and social situations, which can increase your risk for depression. It’s not uncommon for someone with OCD to also have depression. Having one anxiety disorder can increase your odds for having another. Up to80 percentof people with OCD also have major depression episodes. This dual diagnosis is a concern with children, too. Their compulsive behaviors, which may be first developing at a young age, can make them feel unusual. That can lead to withdrawing from friends and can increase the chance of a child developing depression. Depression with psychosis (adsbygoogle = window.adsbygoogle || []).push({});Some individuals who have been diagnosed with major depression may also have symptoms of another mental disorder called psychosis. When the two conditions occur together, it’s known as depressive psychosis. Depressive psychosis causes people to see, hear, believe, or smell things that aren’t real. People with the condition may also experience feelings of sadness, hopelessness, and irritability. The combination of the two conditions is particularly dangerous. That’s because someone with depressive psychosis may experience delusions that cause them to have thoughts of suicide or to take unusual risks. It’s unclear what causes these two conditions or why they can occur together, but treatment can successfully ease symptoms. Treatments include medications and electroconvulsive therapy (ECT). Understanding the risk factors and possible causes can help you be aware of early symptoms. Read more about depressive psychosis, how it’s treated, and what healthcare professionals understand about why it occurs. Depression in pregnancyPregnancy is often an exciting time for people. However, it can still be common for a pregnant woman to experience depression. Symptoms of depression during pregnancy include:
Treatment for depression during pregnancy may focus entirely on talk therapy and other natural treatments. While some women do take antidepressants during their pregnancy, it’s not clear which ones are the safest. Your healthcare provider may encourage you to try an alternative option until after the birth of your baby. The risks for depression can continue after the baby arrives. Postpartum depression, which is also called major depressive disorder with peripartum onset, is a serious concern for new mothers. Recognizing the symptoms may help you spot a problem and seek help before it becomes overwhelming. Depression and alcoholResearch has established a link between alcohol use and depression. People who have depression are more likely to misuse alcohol. Out of the 20.2 million U.S. adults who experienced a substance use disorder, about50 percenthad a co-occurring mental illness. Drinking alcohol frequently can make symptoms of depression worse, and people who have depression are more likely to misuse alcohol or become dependent on it. Preventing depressionDepression isn’t generally considered to be preventable. It’s hard to recognize what causes it, which means preventing it is more difficult. But once you’ve experienced a depressive episode, you may be better prepared to prevent a future episode by learning which lifestyle changes and treatments are helpful. Techniques that may help include:
Other techniques and ideas may also help you prevent depression. Read the full list of 15 ways you may be able to avoid depression. Outlook for depressionDepression can be temporary, or it can be a long-term challenge. Treatment doesn’t always make your depression go away completely. However, treatment often makes symptoms more manageable. Managing symptoms of depression involves finding the right combination of medications and therapies. If one treatment doesn’t work, talk with your healthcare professional. They can help you create a different treatment plan that may work better in helping you manage your condition. Which characteristics would a nurse expect to see in a patient with depression?Hopelessness, helplessness, and/or suicidal ideations.
Which symptom does the nurse observe in a patient in the primary stage of syphilis?Symptoms of primary syphilis are: Small, painless open sore or ulcer (called a chancre) on the genitals, mouth, skin, or rectum that heals by itself in 3 to 6 weeks.
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