Which is a cause of upper airway impairment associated with obstructive sleep apnea Quizlet

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Terms in this set (47)

OSA big picture

Pliable or misproport. large structures in upper airway collapse when airway dilators lose tonic waking input

Collapse causes reduction (hypopnea) or cessation of airflow (apnea) during struggle to breathe against a closed airway

Hypoxia and hypercapnia prompt brieg arousals during which recovery breathing occurs

sleep architecture is disputed and phys stress is increased

OSA= Most common sleep related disorder

Occurs when posterior airspace gets too tight during sleep preventing normal breathing

sleep apnea

Open mouth breathing
tongue collapsed in throat
airway blocked
breathing through the nose and mouth

signs of obstructed breathing

Prevalence of OSA is __________

Daytime impairment symptoms are ________

Increasing

common complaints (fatigue)

link to medical disease

Two main reason to care about OSA

1. DAYTIME NUEROCOGNITIVE IMPAIRMENT
-excessive daytime sleepiness
-add
-fatigue
-somatic sx
-depression
-increased risk of MVA, work problems

2. ELEVATED CARDIOVASCULAR RISK*******
-stong causal links to refractory HTN and atrial fib
-link to stroke,
-chf, MI increased in OSA
-increased CV and All-Cause Mortality

Exploring reason #1 :

common questions to ask?

1. Assessing daytime neurocognitive impairment:

When things slow down during the day do you feel liek you are fighting to stay awake?

how satisfied are you with your sleep?

memory.concentration

ADD

moodiness/depression

The

Subjective way to see if patients are having a sleep problem

The epworth sleepiness scale

Epworth sleepiness scale; pathologic degree?

>10/24 suggests pathologic degree of daytime sleepiness

Exploring reason #2

Refractive HTN
Obesity/ .Metabolic syndrome **********
Hypertension
CHF
CVA
Atrial fib
depression
adhd
insomnia
fibromyalgia
dementia
smoking

How to assess for OSA

Snoring
Witnessed apnea
Subjective awakening w/gasping or SOB
Assess for daytime impairment
UTILIZE SCREENING TOOLS IN HIGH RISK PTS. (STOP BANG)
Evaluate for physical signs of an obstructive upper airway

Physical exam points when assessing for OSA

Nasopharynx

Posterior oropharynx

Exam of nose in OSA

Inferior turbinate hypertrophy
Nasal polyps
Nasal valvular/alar collapse can increase nasal airflow resistance

(LOOK FOR THINGS THAT MAY CREATE DIFFICULTY BREATHING THRU NOSE)

Mouth exam for OSA 7 things

1. Tonsils
2. Estimation of extent of posterior OP crowding
3. soft palate characteristics (inc uvula)
4. tongue size

Friedman Tonsillar Classification

SHOW KNOW EACH PIC and number

0-4+

0= no tonsils visible or surgically absent
1- tonsils are w/in pillars
2+= extend beyond posterior pillars
3+ at least half way to uvula
4+

High arched hard palate suggests? (finish)

Maxillary insufficiency

Crowds

Bilateral posterior maxillary crossbite suggests?

Maxillary insufficiency

Mallampati classification

(assessment of how crowded is the airway- post oropharynx)

Head is neutral, ask pt. to protrude tongue maximally, DO NOT ASK THE PT. TO PHONATE (ahhh)

Class 1: can see all of the soft palate and uvula, easy to visualize the post oropharyngeal wall

class 2: Tip of uvula lies behind tongue

class 3: barely able to see the base of the uvula

class 4: Cannot see anything but hard palate

HIGHER MALLAMPATI HIGHER LIKELIHOOD OF OSA

Crowded posterior oropharynx

...

Retrognathia

The forgotten risk factor for OSA

(tongue closer to posterior oropharynx; when lie down loses normal tone)

Tongue scalloping

May increase likelihood of OSA

Most imp. PHYSICAL predictor of OSA

Large neck circumference

Men 17 inches (31%)
Women 16 inches

Dont neglect the rest of the exam!

General
Obesity
Pallor

CV exam
Sxs of heart failure
rhythm of

DX of OSA Gold standard

Polysomnography - in lab overnight

Data set for Polysomnography

EEG
Electro-oculogram
ECG
Microphone
Digital video/audio recording
thoracic and abdominal effort
EMG leads: chin, legs, intercostal
Nasal pressure transducer and nasal/oral thermister
Body position sensor
Extra info?
More eeg channels
esophageal pressure

Most common metric used to predict future risk from OSA

AHI

(Apnea-hypopnea Index)

AHI >30 is strongly associated with increased all cause mortality

Reported with polysongo reading
SCORING OBSTRUCTIVE EVENTS

AHI <5

AHI 5-14

AHI 15-29

AHI >30

how many times pt. has apnic episode or hyponic episode while on polysono.

No OSA

Mild OSA

Moderate OSA

Severe OSA

AHI_____ is abnormal if CV risk factors or daytime impairment sx present

AHI___ associated with increased long term mortality

****AHI _________
is strongly associated with increased all cause mortality

ahi >5

ahi >15

AHI >30

Symptoms but low AHI still = OSA
cognitive impairment too

...

Higher AHI more likely to die of CARDIOVASCULAR event

...

IMP:

Increased in mortality noted in sleepy and non sleepy patients ***************

(not all pts. w/ sleep apnea will be sleepy the next day)

...

Also consider

...

5 things to think about before order PSG

1. Does this patient have significant circadian misalignment?
-delayed sleep phase
-ICU sleep patterns

2. Is the patient on supp 02

3. Is the patient medically stable?

4. Medications: Will this be representative night?

5. What will you do with the results?

Hint: you can always call your friendly neigh sleep me specialist and as if PSG is app.

How to order a polysomnogram:

Four key pieces of info to tell us..?

...

6 things to consider when crafting a tx plan

1. rationale for disease

2. medical mandate for definitive tx

3. patient anatomy

4. financial considerations

5. response to tx

6. is tx plan acceptable

First line tx for OSA
and other tx options

1st line: CPAP (contin. positive airway pressure)

Weight loss should accompany CPAP

Oral appliances

Position therapy

Surgery

Oxygen

How does CPAP work?

Positive pressure is delivered via one of many interfaces (masks)

Helps posterior oropharynx stay open

Barrier to tx w/ CPAP

Open mouth breathers )

Why should someone use CPAP?

1. improve daytime impairment sx's
2. improve subjective sleep quality
3. decrease long term cardiovas risk
-can improve BP
-can imporve ejection fraction in pts. w/ systolic CHF
4. Improve bed partners sleep

Four questions to ask about CPAP

Are they using it?

Are they tolerating it?

Is it making things better?

Do they truly need it?

CPAP Follow up

Compliance
-how long are you able to keep it on?
-how often are you wearing it?

Tolerability
-rhinitis symps
-dermal discomfort
-mask discomfort
-mouth dryness
-nocturnal mask off
-claustrophobia

Improvement in sleep quality, daytime impairment symptoms

What to do with the patient who doesnt do well with CPAP?

1. determine where the failure takes place

2. re-assess why tx is being recommended**

3. can the problem be worked around?

4. if tx is necessary are there other options

5.

Oral appliances for OSA (slide)

Effective in pts

Surgical tx for OSA

tonsilectomy/adenoidectomy (KEY TX option for pediatrics pts with OSA)

Definitive tx for OSA

Tracheostomy (IF VERY SEVERE)

Other considerations for OSA

Weight loss

Position therapy
Supine predominant

Oxygen
may help decrease hypoxia but does not fix the obstructive events

Which mechanism best describes etiology of OSA

Cardinal feature of OSA

Physical exam finding with highest correlation with OSA

Polysomnogram reading that denotes severe osa

most common treatment of osa

Posterior airway collapse during sleep

Sleepiness, poor concentration, nocturnal snorts

Large neck circumference

AHI of 30 (severity determined by AHI index)

positive airway pressure

a 40 yr old man presents for eval of frequent awakenings at night and daytime fatigue. A polysomnogram is performed and reveals 18 apneic episodes per hour of sleep. What is strongly associated with the dx?

Unstable HTN

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Which is a cause of upper airway impairment associated with obstructive sleep apnea?

In adults, the most common cause of obstructive sleep apnea is excess weight and obesity, which is associated with the soft tissue of the mouth and throat. During sleep, when throat and tongue muscles are more relaxed, this soft tissue can cause the airway to become blocked.

What causes upper airway restriction?

Causes. The airway can become narrowed or blocked due to many causes, including: Allergic reactions in which the trachea or throat swell closed, including allergic reactions to a bee sting, peanuts and tree nuts, antibiotics (such as penicillin), and blood pressure medicines (such as ACE inhibitors)

What breathing disorders are caused by sleep apnea?

Sleep-related breathing disorders or sleep-disordered breathing are characterized by abnormal respiration during sleep. They are grouped into obstructive sleep apnea (OSA), central sleep apnea, sleep-related hypoventilation, and sleep-related hypoxemia disorder.

What is the most common site of upper airway collapse in OSA?

Although the velopharynx was the most common site of obstruction (in 89% of patients), most patients (72%) had multiple sites of obstruction.