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-The nucleoli disappear.
-The mitotic spindle begins to form. It is composed of centrosomes and the microtubules that extend from them.
-The radial arrays of shorter microtubules that extend from the centrosomes are called asters.
-The centrosomes move away from each other, apparently propelled by lengthening microtubules.
-Each of the two chromatids of a chromosome has a kinetochore, a specialized protein structure located at the centromere.
-Kinetochore microtubules from each pole attach to one of two kinetochores.
-Nonkinetochore microtubules interact with those from opposite ends of the spindle.
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